Stent Thrombosis after Rescue Percutaneous Coronary Intervention in Acute ST-Segment Elevation Myocardial Infarction

Khalid Bin Thani1, *, Fajer Al-Moosa1, Eman Murad1, Aisha Al-Moosa1, Mohamed E. Alalawi1, Hind Al-Sindi2
1 Salmaniya Medical Complex, Division of Cardiology, Department of Internal Medicine, Manama, Kingdom of Bahrain
2 Primary Care and Family Physician Program, Ministry of Health, Manama, Kingdom of Bahrain

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© Thani et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (, which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Division of Cardiology, Department of Internal Medicine, Salmaniya Medical Complex, P.O. Box 12, Manama, Kingdom of Bahrain; Tel: (+973) 17-279750; Fax: (+973) 17-279774; E-mail:


Main Problem:

To determine the incidence of coronary stent thrombosis (ST) in patients with acute ST segment elevation myocardial infarction (STEMI) after rescue percutaneous coronary intervention (PCI).


An observational study looking at the incidence of ST in a middle-eastern population. A total of 510 consecutive patients presented with ST-segment elevation myocardial infarction (STEMI) were enrolled and underwent thrombolytic therapy with a total follow-up period of 2 years. Study outcomes were ST, death, re-infarction or acute coronary syndrome requiring coronary angiography and PCI.


A total of 510 patients enrolled, all diagnosed with STEMI and underwent thrombolytic therapy. Only 100 subjects underwent rescue PCI with intra-coronary stenting, including 54 patients with drug-eluting stent (DES) and 46 patients with bare metal stent (BMS). During the study period and follow-up, the overall rate of ST was 13.7%, definite ST occurred in 6 patients (5.5%), probable ST in 8 patients (7.3%), and possible ST in one patient (0.9%), including 0.9% acute ST, 0.9% sub-acute ST, 2.8% late ST and 8.3% very late ST. Patients with ST were likely to have prior PCI (p=0.001), prior coronary artery bypass grafting (CABG) (p=0.002) and history of heart failure (p=0.04).


ST is infrequent event with major consequences in patients presenting with STEMI in the first 2 years after stent implantation.

Keywords: Acute myocardial Infarction, Arab, Bahrain, Gulf States, Middle East, Stent Thrombosis, STEMI.