Midwall Fibrosis: Cardiac Magnetic Resonance Imaging in Risk Stratifying Cardiomyopathies

D.P. Ripley1, 2, *, P. Garg3, A. Kotecha1, O.E. Gosling1, 2, N.G. Bellenger1, 2
1 Royal Devon & Exeter NHS Foundation Trust, Barrack Road, Exeter, EX2 5DW, UK
2 Peninsula College of Medicine & Dentistry, Barrack Road, Exeter, EX2 5DW, UK
3 Sheffield Teaching Hospital NHS Foundation Trust, Herries Road, Sheffield, South Yorks, S5 7AU, UK

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© Ripley et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License ( 3.0/), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Royal Devon & Exeter NHS Foundation Trust, Barrack Road, Exeter, EX2 5DW, UK; Tel: 01392 411 611; Fax: 01392 404 652; E-mail:


The United Kingdom’s National Institute for Health and Care Excellence guidance on implantable cardiac defibrillator (ICD) therapy recommend ICD in those with left ventricular dysfunction and a high risk of sudden cardiac death (SCD). SCD accounts for 30% deaths in non-ischaemic dilated cardiomyopathy (DCM), however risk stratifying and predicting SCD in DCM is a major management challenge. We present two cases demonstrating the potential role of cardiac magnetic resonance imaging in risk stratifying DCM.

Keywords: Magnetic Resonance Imaging, Sudden Cardiac Death, Ventricular Tachycardia, Dilated Cardiomyopathy, Fibrosis.