Design and Rationale of Gulf locals with Acute Coronary Syndrome Events (Gulf Coast) Registry



Mohammad Zubaid*, 1, Khalid Bin Thani 2, Wafa Rashed 3, Alawi Alsheikh-Ali 4, Najib Alrawahi 5, Mustafa Ridha 6, Mousa Akbar 7, Fahad Alenezi 7, Rashed Alhamdan 9, Wael Almahmeed 10, Hussam Ouda 11, Arif Al-Mulla 12, Fahad Baslaib 13, Abdulla Shehab 14, Abdulla Alnuaimi 15, Haitham Amin 16, Harlan M Krumholz 17
1 Department of Medicine, Faculty of Medicine, Kuwait University, Kuwait
2 Salmaniya Medical Complex, Cardiology Unit, Manama, Bahrain
3 Department of Medicine, Mubarak Al-Kabeer Hospital, Ministry of Health, Kuwait
4 Heart and Vascular Institute, Sheikh Khalifa Medical City, Abu Dhabi, UAE; and Tufts University School of Medicine, Boston, MA, USA
5 Royal Hospital, Muscat, Oman
6 Department of Medicine, Al-Adan, Ministry of Health, Kuwait
7 Department of Medicine, Al-Sabah, Ministry of Health, Kuwait
8 Department of Medicine, Farwaniya, Ministry of Health, Kuwait
9 Department of Medicine, Al-Jahra, Ministry of Health, Kuwait
10 Institute of Cardiac Science, Sheikh Khalifa Medical City
11 Tawam Hospital. Alain, UAE
12 Dubai Hospital, Dubai Health Authority, Dubai,UAE
13 Rashid Hospital, Dubai, UAE
14 Alain Hospital, Alain,UAE
15 Zayed Military Hospital, Abu Dhabi, UAE
16 Mohamed Bin Khalifa Cardiac Center
17 Yale University School of Medicine, New Haven, Connecticut, USA


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© Zubaid et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Faculty of Medicine, Health Sciences Centre, Kuwait University, Kuwait, P.O. Box 24923, Safat 13110, Kuwait; Tel: (965) 25319596; Fax: +965-25338907; E-mail: zubaid@hsc.edu.kw


Abstract

Objectives:

To describe the risk profile, management and one-year outcomes of patients hospitalized with acute coronary syndrome (ACS) in the Gulf region of the Middle East.

Subjects and Methods:

The Gulf locals with acute coronary syndrome events (Gulf COAST) registry is a prospective, multinational, longitudinal, observational, cohort-based registry of consecutive citizens, from the Gulf region of the Middle East, admitted from January 2012 to January 2013 to 29 hospitals with a diagnosis of ACS. Data entered online included patient demographics, cardiovascular risk profiles, past medical history, physical findings on admission, in-hospital diagnostic tests and therapeutic management, as well as one year outcomes.

Results:

3188 patients were recruited. The mean age was 60.4 ± 12.6years (range: 22-112), 2104 (66%) were males and 1084 (34%) females. The discharge diagnosis was ST-segment elevation myocardial infarction (STEMI) in 741 (23.2%), new-onset left bundle branch block myocardial infarction (LBBBMI) in 30 (0.9%), non-ST-segment elevation myocardial infarction (NSTEMI) in 1486 (46.6%) and unstable angina in 931 (29.2%). At hospital presentation, 2105 (66%), 1779 (55.8%), 1703 (53.4%) and 740 (23.2%) had history of hypertension, dyslipidemia, diabetes mellitus and active smoking, respectively.

Conclusion:

Patients with ACS in our region are young with very high risk profile. The Gulf COAST registry is an example of successful regional collaboration and will provide information on contemporary management of ACS in the region.

Keywords: Acute coronary syndromes, Gulf, Middle East, registries..