RESEARCH ARTICLE


Dyslipidemia Induced by Drugs Used for the Prevention and Treatment of Vascular Diseases



Konstantinos Tziomalos 1, Vasilios G Athyros 2, Asterios Karagiannis 2, Dimitri P Mikhailidis 1, *
1 Department of Clinical Biochemistry (Vascular Prevention Clinic) and Department of Surgery, Royal Free Campus, University College London Medical School, University College London (UCL), London, UK
2 Second Propedeutic Department of Internal Medicine, Aristotle University, Hippokration Hospital, Thessaloniki, Greece


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© Tziomalos et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Department of Clinical Biochemistry, Royal Free Hospital Campus, University College London Medical School, University College London (UCL), Pond Street, London NW3 2QG, UK; Tel: +44 20 7830 2258; Fax: +44 20 7830 2235; E-mail: MIKHAILIDIS@aol.com


Abstract

Dyslipidemia is a major vascular risk factor. Interestingly, several agents used for the prevention and treatment of vascular diseases have an adverse effect on the lipid profile. In addition, agents belonging to the same class (e.g. beta blockers) can have significantly different actions on lipid levels. We summarize the effects of drugs used for the prevention and treatment of vascular diseases on the lipid profile. These effects should be considered when selecting a specific agent, particularly in high-risk patients.

Keywords:: Dyslipidemia, antihypertensive agents, antidiabetic agents, lipid-modifying agents, antiobesity agents..