RESEARCH ARTICLE


Coronary Artery Disease in an Asymptomatic Population Undergoing a Multidetector Computed Tomography (MDCT) Coronary Angiography



Ghassan Zaid1, Dana Yehudai1, Uri Rosenschein1, Abdel-Rauf Zeina2, 3, *
1 Department of Cardiology, Bnai-Zion Medical Center, Technion Institute of Technology, Faculty of Medicine, Haifa, Israel
2 Department of Radiology and MAR Imaging Institute, Bnai-Zion Medical Center, Technion Institute of Technology, Faculty of Medicine, Haifa, Israel
3 Department of Radiology, Hillel Yaffe Medical Center, Hadera, Israel


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© Zaid et al.; Licensee Bentham Open.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the original work is properly cited.

* Address correspondence to this author at the Department of Radiology, Hillel Yaffe Medical Center, P.O.B. 169, Hadera 38100, Israel; Tel: + 972-4-6304621; Fax: + 972-4-6304884: E-mail: raufzeina3@hotmail.com


Abstract

Aim:

To assess the prevalence of coronary artery disease (CAD) in asymptomatic subjects using multidetector computed tomography (MDCT) and its relationships to demographic and clinical risk factors.

Material and method:

We enrolled consecutive asymptomatic volunteers with no evidence of ischemic heart disease that underwent MDCT for the early detection of CAD. All MDCT findings were correlated with demographic and risk factors. A total of 2820 coro-nary segments were analyzed in 188 asymptomatic subjects (150 males and 38 females), aged 54.4 ± 7.4 years.

Results:

A total of 128 (68%) demonstrated MDCT findings compatible with CAD; of these 111 (86.7%) had non-significant (diameter stenosis ≤ 50%) and 17 (13.3%) had significant CAD (diameter stenosis ≥ 50%). Compared with older subjects (mean age 56±8 years), younger subjects had a lower prevalence of MDCT findings of CAD 55.5% vs. 12.5%, respectively (P<0.001), regardless of risk factors. Males had more CAD (mostly non-significant) compared with females (109 [72.7%] vs. 19 [50.3%], respectively; P= 0.007). Subjects with ≥ 2 risk factors had a higher prevalence of CAD in general and significant CAD in particular (P<0.001).

Conclusion:

CAD in asymptomatic population seems to be not uncommon. Using MDCT a high prevalence of non-significant and low prevalence of significant CAD was discovered in middle age asymptomatic population.

Keywords:: Coronary artery disease, risk factors, multidetector computed tomography..