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Animal Models of Cardiac Disease and Stem Cell Therapy
Lailiang Ou1 , 2
Wenzhong Li2 , *
Yi Liu1
Yue Zhang2
Shen Jie2 , 3
Deling Kong1
Gustav Steinhoff2
Nan Ma2 , 4
Authors Info & Affiliations
Yi Liu1
Yue Zhang2
Shen Jie2 , 3
Deling Kong1
Gustav Steinhoff2
Nan Ma2 , 4
Authors Info & Affiliations
The Open Cardiovascular Medicine Journal
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26 Nov 2010 •
RESEARCH ARTICLE
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DOI: 10.2174/1874192401004010231
Abstract
Animal models that mimic cardiovascular diseases are indispensable tools for understanding the mechanisms underlying the diseases at the cellular and molecular level. This review focuses on various methods in preclinical research to create small animal models of cardiac diseases, such as myocardial infarction, dilated cardiomyopathy, heart failure, myocarditis and cardiac hypertrophy, and the related stem cell treatment for these diseases.
Keywords: Animal model, myocardial infarction, dilated cardiomyopathy, heart failure, myocarditis, cardiac hypertrophy, stem cell..
