Animal Models of Cardiac Disease and Stem Cell Therapy
Lailiang Ou1, 2, #, Wenzhong Li2, #, *, Yi Liu1, #, Yue Zhang2, #, Shen Jie2, 3, #, Deling Kong1, Gustav Steinhoff2, Nan Ma2, 4
Identifiers and Pagination:Year: 2010
First Page: 231
Last Page: 239
Publisher ID: TOCMJ-4-231
Article History:Received Date: 13/9/2010
Revision Received Date: 30/9/2010
Acceptance Date: 4/10/2010
Electronic publication date: 26/11/2010
Collection year: 2010
open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.
Animal models that mimic cardiovascular diseases are indispensable tools for understanding the mechanisms underlying the diseases at the cellular and molecular level. This review focuses on various methods in preclinical research to create small animal models of cardiac diseases, such as myocardial infarction, dilated cardiomyopathy, heart failure, myocarditis and cardiac hypertrophy, and the related stem cell treatment for these diseases.