All published articles of this journal are available on ScienceDirect.
Experimental Models of Abdominal Aortic Aneurysms
The Open Cardiovascular Medicine Journal
•
26 Nov 2010 •
RESEARCH ARTICLE
•
DOI: 10.2174/1874192401004010221
Abstract
Despite being a leading cause of death in the West, the pathophysiology of abdominal aortic aneurysms (AAA) is still incompletely understood. Pharmacotherapy to reduce the growth of small AAAs is limited and techniques for repairing aneurysms continue to evolve. Experimental models play a key role in AAA research, as they allow a detailed evaluation of the pathogenesis of disease progression. This review focuses on in vivo experimental models, which have improved our understanding of the potential mechanisms of AAA development and contributed to the advancement of new treatments.
Keywords: Abdominal aortic aneurysms (AAA), experimental models, elastase infusion. .
