The Value of p-Value in Biomedical Research

Demosthenes B Panagiotakos*
Department of Dietetics - Nutrition, Harokopio University, Athens, Greece

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© Demosthenes B. Panagiotakos; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the 46 Paleon Polemiston St. Glyfada, Attica, 166 74, Greece; Tel: +30210-9603116; Fax: +30210-9600719; E-mail:


Significance tests and the corresponding p-values play a crucial role in decision making. In this commentary the meaning, interpretation and misinterpretation of p-values is presented. Alternatives for evaluating the reported evidence are also discussed.

Key Words: Evidence based medicine, probabilities, p value, biostatistics..