Acute Myocardial Infarction in Young Patients and its Correlation with Obesity Status at Pre-adolescent Stage: A Narrative Review

Maria K. Chrissini1, Demosthenes B. Panagiotakos1, *
1 Department of Nutrition-Dietetics, School of Health Sciences and Education, Harokopio University, Athens, Greece

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© 2022 Chrissini and Panagiotakos

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at Department of Nutrition-Dietetics, School of Health Sciences and Education, Harokopio University, Athens, Greece, Tel. +30 210 9549332; E-mail:



Cardiovascular diseases (CVD), especially acute myocardial infarction (AMI), remain a worldwide major cause of premature morbidity and mortality, with considerable health care costs. Metabolic, behavioural, environmental, and social risk factors are significant drivers of AMI, with obesity being a key determinant among them. Childhood obesity constitutes a major health threat that is considered a global epidemic of the 21st century.


To assess whether excess weight from the first years of life acts as a predisposing factor in increasing the risk of AMI in young adults.


This is a narrative review of the evidence concerning the epidemiology of early AMI and obesity, using PubMed and Google Scholar.


There is substantial evidence showing that excess weight during childhood multiplies the risk of AMI at an early age.


Premature AMI seems to have significant drivers related to lifestyle factors, such as childhood obesity. In the era of a childhood obesity epidemic, the aforementioned relationship underlines the need for early prevention and management.

Keywords: Myocardial infarction, Cardiovascular disease, Ischemic heart disease, Obesity, Childhood, Adolescence.