Outcomes of Patients with Cardiac Myxoma: A Retrospective Multicentre Study

Umit Duman1, *, Cevdet Furat2, Gokhan Keskin3, Dogan Kahraman3, Erhan Hafiz4
1 Koc American Vakfi Hospital, Sisli, Istanbul, Turkey
2 Department of Cardiovascular Surgery, The Health Sciences University, Kecioren Research and Training Hospital, Ankara, Turkey
3 Department of Cardiovascular Surgery, Gaziantep University School of Medicine, Gaziantep, Turkey
4 Department of Cardiovascular Surgery, Adana City Education and Training Hospital, Health Sciences University, Adana, Turkey

© 2019 Duman et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at the Koc American Vakfi Hospital, Sisli, Istanbul, Turkey; Tel: +90 (532) 573 7211; E-mail:



We present a 15-year follow-up of patients with Cardiac Myxoma (CM) who underwent tumour resection.

Patients and Methods:

Between 2001 and 2016, 38 patients with CM were operated on. We retrospectively reviewed, their clinical presentations. We also analysed the echocardiographic, electrocardiographic and pathology reports.


No mortality was seen after surgery. The mean age of the patients was 41.7±7.8 years and the female/male ratio was 22/16. Two patients with CM were children. The main symptoms of left atrial CM were dyspnoea on exertion, chest pain and congestive heart failure. Tricuspid valve pathology, and leg oedema were the main symptoms in patients with right atrial CM combined with right heart failure. CM as a cause of nephrotic syndrome was detected in 2 patients. In 5 asymptomatic patients (13.1%), CM was detected incidentally. We detected a pericardial invasion by the tumour in 1 patient. We performed secondary surgery because of tumour recurrence in 2 patients. Overall, survival for patients after surgical excision was 96.4±1.6% at 1 year, 91.7±2.4% at 5 years, 87.6±2.6% at 10 years and 85±1.9% at 15 years.


The symptoms of CM may include congestive heart failure or nephrotic syndrome. Because CM may be associated with serious cardiac symptoms, tumour excision should be performed immediately after diagnosis. The use of right anterior thoracotomy for CM resection is a safe surgical approach.

Keywords: Cardiac myxoma, Echocardiography, Surgery, Pathologic classification, Cardiac tumour, Heart failure.