The Predictive Value of the Syntax Score in Patients With Chronic Coronary Artery Disease Undergoing Percutaneous Coronary Intervention or Coronary Artery Bypass Grafting: A Pilot Study

K. Papadopoulos1, *, I. Lekakis2, E. Nicolaides3
1 Cardiology Department, Medical Check-up Centre, 21st Costa Anaxagora Street, 2014, Nicosia, Cyprus.
2 Cardiology Department, Attikon University Hospital, Rimini 1, Chaidari 124 62, Athens, Greece.
3 Saint George’s Medical School, University of Nicosia Medical School, 46 Makedonitissas Avenue, Engomi, 1700, Nicosia, Cyprus.

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© 2017 Papadopoulos et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at Cardiology Department, Medical Check-up Centre, 21st Costa Anaxagora Street, 2014, Nicosia, Cyprus; Tel: +35799460314; E-mail:



To evaluate the usefulness of the SYNTAX score (SS) in predicting 1-year clinical outcomes in a population of patients with chronic coronary artery disease (CAD) undergoing percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG).


Despite the proven prognostic value of the SS in patients with multivessel and/or left main (LM) CAD, its usefulness in other patient subsets remains uncertain.


This was a prospective single centre cohort study conducted from September 2012 to November 2014 at the Nicosia General Hospital, Cyprus. Patients (n=140; 94% men and 6% women) with chronic CAD undergoing revascularization with either PCI or CABG were evaluated.


At 1-year, angina occurred in 20 patients (14.3%), myocardial infarction (MI) in 3 patients (2.1%), repeat revascularization procedures in 9 patients (6.4%) and death in 12 patients (8.6%). The SS independently predicted angina (p=0.024) but was not predictive of MI (p=0.964), death (p=0.292) or repeat revascularization (p=0.069).


In this patient population, the SS predicted angina in the year following revascularization but was not predictive of MI, death or repeat revascularization.

Keywords: Coronary artery disease, Percutaneous coronary intervention, Coronary artery bypass grafting, Syntax score, Risk assessment, American Heart Association (AHA).