The Predictive Value of the Syntax Score in Patients With Chronic Coronary Artery Disease Undergoing Percutaneous Coronary Intervention or Coronary Artery Bypass Grafting: A Pilot Study



K. Papadopoulos1, *, I. Lekakis2, E. Nicolaides3
1 Cardiology Department, Medical Check-up Centre, 21st Costa Anaxagora Street, 2014, Nicosia, Cyprus.
2 Cardiology Department, Attikon University Hospital, Rimini 1, Chaidari 124 62, Athens, Greece.
3 Saint George’s Medical School, University of Nicosia Medical School, 46 Makedonitissas Avenue, Engomi, 1700, Nicosia, Cyprus.


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© 2017 Papadopoulos et al.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

* Address correspondence to this author at Cardiology Department, Medical Check-up Centre, 21st Costa Anaxagora Street, 2014, Nicosia, Cyprus; Tel: +35799460314; E-mail: kyriacospap@hotmail.com


Abstract

Objectives:

To evaluate the usefulness of the SYNTAX score (SS) in predicting 1-year clinical outcomes in a population of patients with chronic coronary artery disease (CAD) undergoing percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG).

Background:

Despite the proven prognostic value of the SS in patients with multivessel and/or left main (LM) CAD, its usefulness in other patient subsets remains uncertain.

Methods:

This was a prospective single centre cohort study conducted from September 2012 to November 2014 at the Nicosia General Hospital, Cyprus. Patients (n=140; 94% men and 6% women) with chronic CAD undergoing revascularization with either PCI or CABG were evaluated.

Results:

At 1-year, angina occurred in 20 patients (14.3%), myocardial infarction (MI) in 3 patients (2.1%), repeat revascularization procedures in 9 patients (6.4%) and death in 12 patients (8.6%). The SS independently predicted angina (p=0.024) but was not predictive of MI (p=0.964), death (p=0.292) or repeat revascularization (p=0.069).

Conclusion:

In this patient population, the SS predicted angina in the year following revascularization but was not predictive of MI, death or repeat revascularization.

Keywords: Coronary artery disease, Percutaneous coronary intervention, Coronary artery bypass grafting, Syntax score, Risk assessment, American Heart Association (AHA).