RESEARCH ARTICLE

The Predictive Value of the Syntax Score in Patients With Chronic Coronary Artery Disease Undergoing Percutaneous Coronary Intervention or Coronary Artery Bypass Grafting: A Pilot Study

The Open Cardiovascular Medicine Journal 17 Apr 2017 RESEARCH ARTICLE DOI: 10.2174/1874192401711010028

Abstract

Objectives:

To evaluate the usefulness of the SYNTAX score (SS) in predicting 1-year clinical outcomes in a population of patients with chronic coronary artery disease (CAD) undergoing percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG).

Background:

Despite the proven prognostic value of the SS in patients with multivessel and/or left main (LM) CAD, its usefulness in other patient subsets remains uncertain.

Methods:

This was a prospective single centre cohort study conducted from September 2012 to November 2014 at the Nicosia General Hospital, Cyprus. Patients (n=140; 94% men and 6% women) with chronic CAD undergoing revascularization with either PCI or CABG were evaluated.

Results:

At 1-year, angina occurred in 20 patients (14.3%), myocardial infarction (MI) in 3 patients (2.1%), repeat revascularization procedures in 9 patients (6.4%) and death in 12 patients (8.6%). The SS independently predicted angina (p=0.024) but was not predictive of MI (p=0.964), death (p=0.292) or repeat revascularization (p=0.069).

Conclusion:

In this patient population, the SS predicted angina in the year following revascularization but was not predictive of MI, death or repeat revascularization.

Keywords: Coronary artery disease, Percutaneous coronary intervention, Coronary artery bypass grafting, Syntax score, Risk assessment, American Heart Association (AHA).
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