An Unusual Case of Fibromuscular Dysplasia with Bilateral Renal Macroaneurysms: Three-year Outcome After Endovascular Treatment

Roberta Buso1, 2, Marcello Rattazzi 1, 2, Matteo Leoni1, 2, Massimo Puato1 , Francesco Di Paola3 , Paolo Pauletto1, 2, *
Department of Medicine, University of Padova, Italy
Medicina Interna I^, Ca’ Foncello Hospital, Azienda ULSS 9, Treviso, Italy
Neuroradiology Unit, Ca’ Foncello Hospital, Azienda ULSS 9, Treviso, Italy

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© Buso et al.; Licensee Bentham Open.

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* Address correspondence to this author at the Department of Medicine, University of Padova, Medicina Interna I^, Ospedale Ca’ Foncello,Via Ospedale 1, 31100 Treviso, Italy; Tel: +390498211867; +390422322207; Fax:+390498754179; E-mail:


Fibromuscular dysplasia (FMD) is an idiopathic, segmental, non-inflammatory and non-atherosclerotic disease that affects arterial walls, leading to stenosis of small and medium-sized arteries. FMD mostly involves renal and intracranial arteries and only in few patients is associated with macroaneurysms (RAAs). We present the case of a 45-years old woman with recent history of grade 2 hypertension that suffered of subarachnoid haemorrhage due to rupture of a basilar artery aneurysm. The cerebral aneurysm was immediately treated by coil embolization and an abdominal angio-CT scan was performed to investigate the presence of renovascular hypertension. The exam showed the presence of FMD of the renal arteries associated with presence of bilateral RAAs. Due to the high risk of rupture, the bigger aneurysm (2,5 cm diameter) present on the left artery was immediately treated by coil embolization. The fusiform aneurysm, present on the right renal artery, was instead treated one year later by using two flow diverter stents. After three years, an angiographic study showed that both cerebral and renal aneurysms were excluded from the blood flow without evidence of arterial restenosis.

Keywords: fibromuscular dysplasia, bilateral renal macroaneurysms, hypertension, endovascular treatment..