Characteristics of Heart Rate Reduction with Resumption of Supine Position in the Postural Tachycardia Syndrome: Factors Influencing Recovery



Kenneth A Mayuga, Christopher E Gaw, Curtis Tatsuoka , Fetnat Fouad-Tarazi
Heart and Vascular Institute, Dept. of Cardiovascular Medicine, Cleveland Clinic, 9500 Euclid Ave, Desk J2-2, Cleveland, OH 44195, USA


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© Mayuga et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Heart and Vascular Institute, Dept. of Cardiovascular Medicine, Cleveland Clinic, 9500 Euclid Ave, Desk J2-2, Cleveland, OH 44195, USA; Tel: 216-444-5828; Fax: 216-445-3102; E-mail: fouadtf@ccf.org


Abstract

Objectives:

Postural orthostatic tachycardia syndrome (POTS), a heart rate (HR) rise with upright positioning, is dependent on autonomic influences. HR recovery (HR decrease after exercise cessation) is a measure of autonomic function. Characteristics of HR reduction during supine Recovery after head-up Tilt in POTS patients have not been elucidated.

Methods:

113 subjects (mean age 41.7 years, 86 female), diagnosed with POTS on head-up Tilt were analyzed. HR’s were recorded during baseline supine position, 70-degree Tilt, and 20 sec, 1 min and 2 min of supine Recovery. Percent HR reduction during Recovery was calculated.

Results:

Baseline HR was 68.7±13.4 bpm. Maximum HR during Tilt was 109±16.9 bpm. Mean HR was 84.2±20 bpm at 20 sec, 78.5±18.9 bpm at 1-min, and 77.1±18.3 bpm at 2 min of Recovery. Younger age and slower baseline HR were associated with greater HR reductions at 20 sec (p=0.006, p=0.000, respectively). Younger age, slower baseline HR and less time to achieve POTS were associated with greater HR reductions at 1 min (p=0.025, p=0.000, p=0.000, respectively) and at 2 min (p=0.004, p=0.000, p=0.000, respectively). Gender and baseline blood pressures were not significant.

Conclusions:

In POTS patients, HR quickly decreases upon resuming supine position. Younger age, slower baseline HR and less time to achieve POTS were associated with greater HR reductions during supine Recovery. Further study is needed to determine mechanisms, as well as analyze differences in symptoms or prognosis.

Keywords: Heart Rate Recovery, Postural Orthostatic Tachycardia Syndrome, Tilt Table Test, Syncope..