Rosuvastatin was Effective in Acute Heart Failure and Slow Coronary Flow: A Hypothesis-generating Case Report

Arrivi , Alessio; Tanzilli , Gaetano; Puddu , Paolo Emilio; Iannucci , Luca; Mangieri , Enrico

Rosuvastatin was Effective in Acute Heart Failure and Slow Coronary Flow: A Hypothesis-generating Case Report

Alessio Arrivi ¹, Gaetano Tanzilli ², Paolo Emilio Puddu ^{2
, *}, Luca Iannucci ², Enrico Mangieri ²

¹ From the Interventional Cardiology Unit, Santa Maria University Hospital, Terni, Italy

² From the Department of Cardiovascular, Respiratory, Nephrological, Anesthesiological and Geriatrical Sciences, Sapienza University of Rome, Italy

Article Information

Identifiers and Pagination:

Year: 2013
Volume: 7
First Page: 12
Last Page: 15
Publisher ID: TOCMJ-7-12
DOI: 10.2174/1874192401307010012

Article History:

Received Date: 6/8/2012
Acceptance Date: 1/9/2012
Electronic publication date: 31/1/2013
Collection year: 2013

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© Arrivi et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

^* Address correspondence to this author at the Sapienza University of Rome, Department of Cardiovascular, Respiratory, Nephrological, Anesthesio-logical and Geriatrical Sciences, Laboratory of Biotechnologies Applied to Cardiovascular Medicine, Viale del Policlinico, 155, Rome 00161, Italy.; Tel: +39-0649972659; Fax: +39-064453891; E-mail: paoloemilio.puddu@uniroma1.it

Slow coronary flow phenomenon (SCFP) is characterized by angiographically normal coronary arteries with delayed run-off of contrast medium across the vasculature. Its etiology and clinical significance are still not completely known; however, acute congestive heart failure (CHF) is rare in this context. A 71 year-old woman with SCFP presented with acute CHF complicated by ventricular tachycardia. Treated with rosuvastatin (20 mg/day for 6 days) and inotropic drug infusion she had a complete recovery of left ventricular function and normalization of serum levels of the high-sensitivity C-reactive protein (hs-CRP), which were increased (3.6 mg/L) during the acute phase. This case illustrates that the anti-inflammatory properties of rosuvastatin may deserve specific clinical tests not only during the chronic phase but also in the acute phase of CHF patients.

Keywords: Rosuvastatin, acute heart failure, slow coronary flow..

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CASE REPORT

Rosuvastatin was Effective in Acute Heart Failure and Slow Coronary Flow: A Hypothesis-generating Case Report

Article Information

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Article History:

Article Metrics

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Abstract

Track Your Manuscript

Published Contents

About the Editor

About the Journal

The Open Cardiovascular Medicine Journal

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