Ultrasound-Guided Placement of a Renal Artery Stent Using an Intracardiac Probe for Transvascular Imaging
Marek Belohlavek1, *, Panupong Jiamsripong1, Eileen M McMahon1, Theresa R Lombari1, Lilach O Lerman2
Identifiers and Pagination:Year: 2011
First Page: 215
Last Page: 217
Publisher ID: TOCMJ-5-215
Article History:Received Date: 24/6/2011
Revision Received Date: 5/7/2011
Acceptance Date: 6/7/2011
Electronic publication date: 3/11/2011
Collection year: 2011
open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
In this set of images obtained during an experimental study using a porcine animal model, we introduce ultrasound guidance of percutaneous transluminal renal angioplasty and renal stenting. A state-of-the-art intracardiac ultrasound catheter is used here for transvascular scanning from within the lumen of the abdominal aorta, thus providing a field of view for navigation of a balloon catheter and a wire coil (“stent”) into each renal artery of a pig. This study is intended as a contribution to the growing field of minimally invasive interventions and their navigation by non-ionizing ultrasound imaging.
Percutaneous transluminal renal angioplasty and stenting have revolutionized treatment of renal artery stenoses . These procedures are routinely done under fluoroscopic guidance, which can involve substantial radiation exposure. In this proof-of-concept experimental animal study, we demonstrate the feasibility of guiding stent placement by a 10F AcuNav ultrasound catheter (Siemens Medical, Mountain View, CA), which was connected through a SwiftLink cable to a Siemens Sequoia C256 ultrasound system. The AcuNav ultrasound catheter was primarily developed for intracardiac imaging applications, but has also been shown well suitable for transvascular imaging . The purpose of this report was to introduce and illustrate navigation of renal artery stent placement by transvascular ultrasound imaging.
This study was approved by the Mayo Clinic Institutional Animal Care and Use Committee. An adult pig was anesthetized and the AcuNav ultrasound catheter inserted into the left femoral artery and advanced into the abdominal aorta until the kidney and renal artery Fig. (1A) on one side were identified. Then, an angulated-tip 8F Convoy catheter (EP Technologies, Boston Scientific, San Jose, CA) was inserted via the right femoral artery and advanced until its tip appeared within the ultrasound image. The tip was then easily guided into the renal artery orifice Fig. (1B). Subsequently, we inserted into the renal artery Fig. (2A) through the Convoy catheter lumen a PTCA catheter (Charger™; Cordis Corporation, Miami, FL) bearing a 23-gauge copper wire balloon-expandable coil-stent, as previously used experimentally . We inflated and deflated the balloon, and removed
Postmortem photograph showing copper coils placed within right and left renal artery lumens. The insert is a close-up view of the coil inside the right renal artery just after dissecting its orifice.
both catheters, leaving the expanded coil deployed in the renal artery wall Fig. (2B). We repeated the procedure in the contralateral renal artery. At the end of the surgery, postmortem dissections documented successful coil placement inside each renal artery Fig. (3).
To our knowledge, this is the first transvascular ultrasound-guided placement of a renal artery stent by using an intracardiac ultrasound probe.
CONFLICT OF INTEREST
We thank Naomi Gades, DVM, and Ronald Marler, DVM, PhD, for helpful discussions, Danielle Wright for secretarial work, and Ronald Buono, RDCS, for technical assistance. We are also grateful to Siemens Medical Solutions for loan of their SwiftLink cable for connection of our AcuNav catheter to a Siemens Sequoia C256 ultrasound system. Dr. Belohlavek was supported by NIH Grant EB009111.