Aminaphtone for Light Bleeding in Patients Under Oral Anticoagulation

José Maria Pereira de Godoy1, *, Gustavo Paludetto2, Bianca R Testoni2, Priscilla Yukiko Sano2
1 Angiology and Vascular Surgery Service of the Medicine School in São José do Rio Preto- SP (FAMERP)
2 Resident of the Angiology and Vascular Surgery Service of the Medicine School in São José do Rio Preto-SP (FAMERP)

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Creative Commons License
© Pereira de Godoy; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this Author at the Rua Floriano Peixoto, 2950.São José do Rio Preto, SP – Brazil; Zipe code: 15010-020; Tel: 55-17 32326362; Fax: 55-17 32326362; E-mail:



Bleeding is a common complication of oral anticoagulation therapy.


The present study evaluated the use of aminaphtone in patients with minor bleeding while taking warfarin.


Seven patients suffering from bleeding of the nose and gums, who were taking therapeutic doses of warfarin, were included in the study.


The patients were prescribed 75 mg aminaphtone twice daily. For 5 of these patients the bleeding was controlled within 48 h, for 1, within 96 h and for the other, a satisfactory reduction was obtained.


Patients with minor bleeding during treatment using oral anticoagulation, who are free from risk of other complications, can benefit from the use of aminaphtone as an initial therapeutic option.

Keywords: Bleeding, Oral Anticoagulation, Warfarin, Aminaphtone, Treatment .