RESEARCH ARTICLE


Quantitative Evaluation of the Amount of Delayed Myocardial Enhancement as a Predictor of Systolic Dysfunction



J.E Shriki1, K Surti1, A Farvid2, J.S Shinbane2, P.M Colletti1, 2, *
1 Departments of Radiology, Keck School of Medicine, University of Southern, California, USA
2 Departments of Medicine, Keck School of Medicine, University of Southern, California, USA


© Shriki et al.; Licensee Bentham Open.

open-access license: This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the MRI Fellowship Chief of MRI, LAC+USC Imaging Science Center, 1744 Zonal Ave. Los Angeles, CA 90033, USA; Tel: 323-221-2744; Fax: 323-221-2982; E-mail: colletti@usc.edu


Abstract

30 patients with delayed contrast enhancement in patterns suggestive of myocardial infarctions were reviewed. Infarct mass was quantitatively measured using short axis images obtained in the delayed phase of gadopentetate administration. Left ventricular mass and ejection fraction were measured using short axis, steady state free precession images. A relationship is drawn between increased mass of infarction and decreased left ventricular ejection fraction. For each gram of infarct, there is a 0.5 % reduction in ejection fraction (EF = 50 - (0.48 x gm infarcted myocardium); r2= 0.49). For each % increase of infarcted myocardium, there is a 0.67 % reduction in ejection fraction (EF = 50 - (0.67 x percent of infarcted myocardium); r2= 0.39). Left ventricular ejection fraction correlates inversely with the mass of myocardium with delayed enhancement on cardiac MRI.