An Overview of Cardiac Management in Neuromuscular Disease



Renee M. Hickey, John D. Cullen, George M. Sachs*
Department of Neurology, Brown University, Providence, Rhode Island, 02912, USA


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© Hickey et al.; Licensee Bentham Open.

open-access license: This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.

* Address correspondence to this author at the Department of Neurology, Brown University, Providence, Rhode Island, 02912, USA; Tel: (401) 444-8761; Fax: (401) 444-3205; Email: gsachs@lifespan.org


Abstract

Muscular dystrophy and myasthenia gravis are two neuromuscular disorders that can involve significant cardiovascular complications. The frequency and severity of cardiac pathology varies widely among the muscular dystrophies. In some, it is nearly inevitable and requires regular evaluation. In others, assessment of cardiac function can be more symptom-driven. On-ly a minority of myasthenic patients manifest disease-related cardiovascular complications; however, their presentation can be rapidly progressive and life-threatening..

Keywords: Arrythmia, cardiomyopathy, muscular dystrophy, myasthenia gravis, myotonic dystrophy, treatment.